Weekly Case Studies

In both of these clinical case studies, T2Bacteria identified the causative pathogen days sooner than blood culture and allowed for the earlier initiation of targeted therapy.

Targeted Antibiotic Therapy in Endocarditis Case with T2Bacteria

A T2Bacteria result facilitated the diagnosis of infective endocarditis that led to the rapid initiation of targeted antibiotic therapy in a critically ill patient with prosthetic valve endocarditis. Fast species ID enabled targeted treatment 8 days before blood culture results were available.

Detection of Polymicrobial Infection in Critically Ill COVID-19 Patient

T2Bacteria enabled the detection of polymicrobial infection and the detection of a subsequent Enterococcus faecium infection in a patient where cultures remained negative. Rapid species identification led to targeted therapy and eventual discharge.

Secondary Candidemia in Critically Ill COVID-19 Patient

T2Candida enabled the detection of candidemia 29 hours before a positive blood culture was returned. Early detection allowed for the rapid initiation of antifungal therapy in a critically ill COVID-19 patient.

T2Bacteria Identifies Causative Pathogen in a Critically Ill Patient with a Respiratory Infection

A 20-year-old patient with a history of lupus presented to the emergency department with shortness of breath.

Discussion

This case highlights the benefit of T2Bacteria’s rapid bacterial species identification, which enabled early identification of the causative pathogen in a critically ill, immunocompromised patient. Bacterial infections commonly occur following the successful treatment of viral infections. These infections are often missed due to prior antimicrobial use, especially in at-risk patient populations, leading to treatment delays and negative clinical outcomes.

Utilizing T2Candida Result to Impact Appropriate Therapy

A 67-year-old patient had experienced infections, including multi-drug resistant pneumonia, sepsis, and C. difficile colitis during admission.

Discussion

This case highlights the benefit of T2Candida’s rapid fungal species identification, which allowed for the continuation of appropriate antifungal therapy as well as the discontinuation of unnecessary broad-spectrum antibiotics, resulting in clinical improvement.

T2Bacteria Result Used to Alter Therapy

An elderly patient presented to the ED with a day-long history of fever, shaking, suprapubic pain, vomiting, and diarrhea

Discussion

This case highlights not only T2Bacteria’s ability of rapid identification but also the capability to detect the causative organism and use the result to de-escalate therapy.

T2Bacteria for the Diagnosis of Culture-Negative Infective Endocarditis

Faster Targeted Therapy with the T2Bacteria Detection of a Polymicrobial Infection

Avoidance of Inappropriate De-escalation with T2Candida

Faster Time to Targeted Therapy with T2Bacteria

Targeted Antibiotic Therapy in Endocarditis Case with T2Bacteria

Detection of Polymicrobial Infection in Critically Ill COVID-19 Patient

Secondary Candidemia in Critically Ill COVID-19 Patient

T2Bacteria Identifies Causative Pathogen in a Critically Ill Patient with a Respiratory Infection

Discussion

Utilizing T2Candida Result to Impact Appropriate Therapy

Discussion

T2Bacteria Result Used to Alter Therapy

Discussion

T2 BIOSYSTEMS OVERVIEW

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